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The magnitude of reduction tablets in blood pressure with amlodipine is also correlated with the height of pretreatment elevation; thus, individuals with moderate hypertension ( diastolic pressure 105-114 mmHg) had about a 50 greater response than patients with mild hypertension (diastolic pressure 90-104 mmHg). The reported adverse reactions were generally mild and seldom led to discontinuation of treatment (2.6 for Azor and.8 for placebo). In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant tablets disease or other drug therapy. Once daily administration produced statistically significant placebo-corrected reductions in supine and standing blood pressures at 24 hours post-dose, averaging about 12/6 mmHg in the standing position and 13/7 mmHg in the supine position in patients with mild to moderate hypertension. 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